A novel method of 3D printing integrates PLA and TPU to create tissue scaffolds, as reported by 3DPrinting.com.

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Are you interested in the fascinating world of tissue engineering and biomaterials? Well, we have some exciting news for you! Researchers from Monash University in Australia and the Arts et Métiers Institute of Technology in France have made a groundbreaking discovery in tissue engineering. Their findings were recently published in the esteemed Advanced Functional Materials journal, and the implications are astounding.

Traditionally, scientists have struggled to recreate intricate biological structures while simultaneously promoting cell growth. However, this new study presents a revolutionary two-step approach that combines top-down co-extrusion and bottom-up 3D printing techniques. The result? Biomaterials with complex layered architecture that can mimic the structures found in the human body.

So, how does it work? The researchers used a process called multilayer co-extrusion to produce alternating layers of two different materials: biodegradable poly(lactic acid) (PLA) and elastic thermoplastic polyurethane (TPU). Then, they utilized 3D printing technology to construct sophisticated tissue engineering scaffolds. The key to the success of this method lies in maintaining the layered structure during printing, which creates continuous interfaces between the polymer phases.

By adjusting the co-extrusion process, the researchers were able to create filaments with varying layer thicknesses. This allowed them to build 3D constructs with nanoscale polymer layers, resulting in enhanced mechanical properties for certain architectures. The combination of PLA and TPU strengths proved to be extremely beneficial.

But the implications of this study go beyond improved biomaterials. The researchers also explored the impact of their technique in cardiac tissue engineering. The multilayered scaffolds influenced the alignment, morphology, and functionality of rat heart muscle cells known as cardiomyocytes. As we all know, optimal growth and function of cardiomyocytes are crucial for heart health.

Moreover, the innovative fusion of fabrication techniques showcased in this study offers a versatile approach applicable to various tissue engineering endeavors. From bone regeneration to wound healing, the potential applications of this research are immense.

If you’re interested in diving deeper into the science, you can read the full paper titled “Fabrication of Architectured Biomaterials by Multilayer Co-Extrusion and Additive Manufacturing” at this link.

We would love to hear your thoughts on this groundbreaking research! Join the conversation on our Facebook, Twitter, and LinkedIn pages. And don’t forget to sign up for our weekly additive manufacturing newsletter to stay updated on the latest stories in the field. Exciting times lie ahead in the world of tissue engineering, and we’re thrilled to be on this journey with you!

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